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Senescence induction; a possible cancer therapy
Cellular immortalization is a crucial step during the development of human cancer. Primary mammalian cells reach replicative exhaustion after several passages in vitro, a process called replicative senescence. During such a state of permanent growth arrest, senescent cells are refractory to physiolo...
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631463/ https://ncbi.nlm.nih.gov/pubmed/19133111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-3 |
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