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Genetic evidence that FGFs play an instructive role in limb proximal-distal patterning
Half a century ago the apical ectodermal ridge (AER) at the distal tip of the tetrapod limb bud was shown to produce signals necessary for development along the proximal-distal (P-D) axis, but how these signals influence limb patterning is still much debated1,2. FGF gene family members are key AER-d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631409/ https://ncbi.nlm.nih.gov/pubmed/18449196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06876 |
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