Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling

An increase in intracellular calcium concentration is one of the major initial steps in B cell activation following antigen receptor (BCR) ligation. We show herein that in C57BL/6 murine B lymphocytes and in model cell lines, BCR-mediated calcium ion (Ca(2+)) influx occurs via highly selective Ca(2+...

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Main Authors: Lyubchenko, Taras, Nielsen, J. Paul, Miller, Sara M., Liubchenko, Ganna A., Holers, V. Michael
Format: Artigo
Sprog:Inglês
Udgivet: The Society for Leukocyte Biology 2009
Fag:
Receptors, Signal Transduction, and Genes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631365/
https://ncbi.nlm.nih.gov/pubmed/19028960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0308193
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