The Krebs Cycle and Mitochondrial Mass Are Early Victims of Endothelial Dysfunction: Proteomic Approach

Endothelial cell dysfunction is associated with bioavailable nitric oxide deficiency and an excessive generation of reactive oxygen species. We modeled this condition by chronically inhibiting nitric oxide generation with subpressor doses of N(G)-monomethyl-l-arginine (L-NMMA) in C57B6 and Tie-2/gre...

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Detalhes bibliográficos
Main Authors: Addabbo, Francesco, Ratliff, Brian, Park, Hyeong-Cheon, Kuo, Mei-Chuan, Ungvari, Zoltan, Ciszar, Anna, Krasnikof, Boris, Sodhi, Komal, Zhang, Fung, Nasjletti, Alberto, Goligorsky, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631316/
https://ncbi.nlm.nih.gov/pubmed/19095954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080650
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