Detection of Epithelial Cell Injury and Quantification of Infection in the HCT8 Organoid Model of Cryptosporidiosis

Intestinal cells grown in microgravity produce a three-dimensional tissue assembly or “organoid” similar to the human intestinal mucosa, making it an ideal model for enteric infections such as cryptosporidiosis. METHODS: HCT8 cells were grown in a reduced-gravity, low-shear, rotating wall vessel (RW...

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Auteurs principaux: Warren, Cirle Alcantara, Destura, Raul V, Sevilleja, Jesus Emmanuel A D, Barroso, Luis F, Carvalho, Humberto, Barrett, Leah J, O’Brien, Alison D, Guerrant, Richard L
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631281/
https://ncbi.nlm.nih.gov/pubmed/18498239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/588819
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