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The Basic Helix-Loop-Helix Transcription Factor Olig2 Is Critical for Reactive Astrocyte Proliferation after Cortical Injury

The mechanisms underlying the formation of the glial scar after injury are poorly understood. In this report, we demonstrate that after cortical injury Olig2 is upregulated in reactive astrocytes coincident with proliferation of these cells. Short-term lineage tracing studies with glial subtype-rest...

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Detalhes bibliográficos
Main Authors: Chen, Ying, Miles, Darryl K., Hoang, ThaoNguyen, Shi, Jian, Hurlock, Edward, Kernie, Steven G., Lu, Q. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631240/
https://ncbi.nlm.nih.gov/pubmed/18945906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3545-08.2008
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