Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site

BACKGROUND: Catalytic domains of Type II restriction endonucleases (REases) belong to a few unrelated three-dimensional folds. While the PD-(D/E)XK fold is most common among these enzymes, crystal structures have been also determined for single representatives of two other folds: PLD (R.BfiI) and ha...

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Bibliografiske detaljer
Main Authors: Kaminska, Katarzyna H, Kawai, Mikihiko, Boniecki, Michal, Kobayashi, Ichizo, Bujnicki, Janusz M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630997/
https://ncbi.nlm.nih.gov/pubmed/19014591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-48
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