Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy

BACKGROUND: Mathematical models based on kinetics of HIV-1 plasma viremia after initiation of combination antiretroviral therapy (cART) inferred HIV-infected cells to decay exponentially with constant rates correlated to their strength of virus production. To further define in vivo decay kinetics of...

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Autores principales: Fischer, Marek, Joos, Beda, Niederöst, Barbara, Kaiser, Philipp, Hafner, Roland, von Wyl, Viktor, Ackermann, Martina, Weber, Rainer, Günthard, Huldrych F
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630982/
https://ncbi.nlm.nih.gov/pubmed/19036147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-107
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