Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through multi-target mechanisms, including inhibition of topoisomerase I, interaction with DNA and direct effects on mitochondr...

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Autori principali: Baunbæk, Dianne, Trinkler, Nolwenn, Ferandin, Yoan, Lozach, Olivier, Ploypradith, Poonsakdi, Rucirawat, Somsak, Ishibashi, Fumito, Iwao, Masatomo, Meijer, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630805/
https://ncbi.nlm.nih.gov/pubmed/19172192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md20080026
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