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Demonstration of A Multi-step Mechanism for Assembly of the SRP-SRP Receptor Complex: Implications for the Catalytic Role of SRP RNA
Two GTPases in the signal recognition particle (SRP) and its receptor (SR) control the delivery of newly synthesized proteins to the ER or plasma membrane. During the protein targeting reaction, the 4.5S SRP RNA accelerates the association between the two GTPases by 400-fold. Using fluorescence reso...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630804/ https://ncbi.nlm.nih.gov/pubmed/18617187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.049 |
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