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Thermal Nociception and TRPV1 Function are Attenuated in Mice Lacking the Nucleotide Receptor P2Y(2)
Recent studies indicate that ATP and UTP act at G protein-coupled (P2Y) nucleotide receptors to excite nociceptive sensory neurons; nucleotides also potentiate signaling through the pro-nociceptive capsaicin receptor, TRPV1. We demonstrate here that P2Y(2) is the principal UTP receptor in somatosens...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630699/ https://ncbi.nlm.nih.gov/pubmed/18343036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.01.026 |
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