Human UBN1 Is an Ortholog of Yeast Hpc2p and Has an Essential Role in the HIRA/ASF1a Chromatin-Remodeling Pathway in Senescent Cells

Cellular senescence is an irreversible proliferation arrest, tumor suppression process and likely contributor to tissue aging. Senescence is often characterized by domains of facultative heterochromatin, called senescence-associated heterochromatin foci (SAHF), which repress expression of proliferat...

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Главные авторы: Banumathy, Gowrishankar, Somaiah, Neeta, Zhang, Rugang, Tang, Yong, Hoffmann, Jason, Andrake, Mark, Ceulemans, Hugo, Schultz, David, Marmorstein, Ronen, Adams, Peter D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630694/
https://ncbi.nlm.nih.gov/pubmed/19029251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01047-08
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