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Bcl-2 turns deadly
Small-molecule inhibitors of anti-apoptotic Bcl-2 proteins and BH3 mimetic peptides are promising anticancer agents. A recent study identifies a Nur77-based peptide that converts anti-apoptotic Bcl-2 proteins into proapoptotic molecules, providing another potential cancer therapeutic strategy.
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630477/ https://ncbi.nlm.nih.gov/pubmed/19008882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio1208-722 |
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