Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 after Escherichia coli LPS Stimulation of PHA-Cultured PBMCs

Chronic brucellosis patients display a defective Th1 response to PHA. We have previously shown that heat-killed B. abortus (HKBA) can downregulate the PHA-induced increase of CD4+/CD25+ and CD14+/CD80+ cells of brucellosis patients. In the present study, we investigate the effect of E. coli LPS, as...

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Bibliographic Details
Main Authors: Skendros, Panagiotis, Sarantopoulos, Alexandros, Tselios, Konstantinos, Boura, Panagiota
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2008
Subjects:
Clinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630417/
https://ncbi.nlm.nih.gov/pubmed/19190764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/327346
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