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CD40–CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4(+) T cells

IL-17-producing CD4(+) T cells have been recognized as key players in organ-related autoimmune disease; however, the parameters that govern their development are yet to be elucidated fully. By using both in vivo and in vitro systems, we have investigated the role of antigen dose, pathogen-associated...

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Detalhes bibliográficos
Main Authors: Iezzi, Giandomenica, Sonderegger, Ivo, Ampenberger, Franziska, Schmitz, Nicole, Marsland, Benjamin J., Kopf, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630101/
https://ncbi.nlm.nih.gov/pubmed/19136631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810769106
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