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A G-protein γ subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae

The Gpg1 protein is a Gγ subunit mimic implicated in the G-protein glucose-signaling pathway in Saccharomyces cerevisiae, and its function is largely unknown. Here we report that Gpg1 blocks the maintenance of [PSI(+)], an aggregated prion form of the translation termination factor Sup35. Although t...

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Bibliografske podrobnosti
Main Authors: Ishiwata, Masao, Kurahashi, Hiroshi, Nakamura, Yoshikazu
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630093/
https://ncbi.nlm.nih.gov/pubmed/19129493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808383106
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