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A G-protein γ subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae
The Gpg1 protein is a Gγ subunit mimic implicated in the G-protein glucose-signaling pathway in Saccharomyces cerevisiae, and its function is largely unknown. Here we report that Gpg1 blocks the maintenance of [PSI(+)], an aggregated prion form of the translation termination factor Sup35. Although t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630093/ https://ncbi.nlm.nih.gov/pubmed/19129493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808383106 |
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