Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

Hemophilia A is caused by mutations within the Factor VIII (FVIII) gene that lead to depleted protein production and inefficient blood clotting. Several attempts at gene therapy have failed for various reasons—including immune rejection. The recent generation of induced pluripotent stem (iPS) cells...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xu, Dan, Alipio, Zaida, Fink, Louis M., Adcock, Dorothy M., Yang, Jianchang, Ward, David C., Ma, Yupo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630078/
https://ncbi.nlm.nih.gov/pubmed/19139414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812090106
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