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Synthesis and Anticancer Activity Comparison of Phenylalkyl Isoselenocyanates with Corresponding Naturally Occurring and Synthetic Isothiocyanates

Synthesis and identification of novel phenylalkyl isoselenocyanates (ISCs), isosteric selenium analogs of naturally occurring phenylalkyl isothiocyanates (ITCs), as effective cytotoxic and anti-tumor agents is described. The structure-activity relationship comparison of ISCs with ITCs and effect of...

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Detalhes bibliográficos
Main Authors: Sharma, Arun K., Sharma, Arati, Desai, Dhimant, Madhunapantula, SubbaRao V., Huh, Sung Jin, Robertson, Gavin P., Amin, Shantu
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629797/
https://ncbi.nlm.nih.gov/pubmed/19053750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800993r
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