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A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development

Plasmodium falciparum encodes a single calpain that has a distinct domain composition restricted to alveolates. To evaluate the potential of this protein as a drug target, we assessed its essentiality. Both gene disruption by double cross-over and gene truncation by single cross-over recombination f...

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מידע ביבליוגרפי
Main Authors: Russo, Ilaria, Oksman, Anna, Vaupel, Barbara, Goldberg, Daniel E.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629787/
https://ncbi.nlm.nih.gov/pubmed/19164769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806926106
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