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Calmodulin Inhibitory Activity of the Malbrancheamides and Various Analogs

[Image: see text] The preparation and biological activity of various structural analogs of the malbrancheamides are disclosed. The impact of indole chlorination, C-12a relative stereochemistry, and bicyclo[2.2.2]diazaoctane core oxidation state on the ability of these analogs to inhibit calmodulin d...

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Autors principals: Miller, Kenneth A., Figueroa, Mario, Valente, Meriah W. N., Greshock, Thomas J., Mata, Rachel, Williams, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629606/
https://ncbi.nlm.nih.gov/pubmed/18986806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.10.057
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