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Interpretation of Genetic Association Studies: Markers with Replicated Highly Significant Odds Ratios May Be Poor Classifiers

Recent successful discoveries of potentially causal single nucleotide polymorphisms (SNPs) for complex diseases hold great promise, and commercialization of genomics in personalized medicine has already begun. The hope is that genetic testing will benefit patients and their families, and encourage p...

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Detalhes bibliográficos
Main Authors: Jakobsdottir, Johanna, Gorin, Michael B., Conley, Yvette P., Ferrell, Robert E., Weeks, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629574/
https://ncbi.nlm.nih.gov/pubmed/19197355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000337
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