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Endocannabinoid signalling depends on the spatial pattern of synapse activation

The brain's endocannabinoid retrograde messenger system decreases presynaptic transmitter release1,2, but its physiological function is uncertain. We show that endocannabinoid signalling is absent when spatially dispersed synapses are activated on rodent cerebellar Purkinje cells, but that it r...

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Detalhes bibliográficos
Main Authors: Marcaggi, Païkan, Attwell, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629534/
https://ncbi.nlm.nih.gov/pubmed/15864304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1458
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