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Cryptophane Xenon-129 Nuclear Magnetic Resonance Biosensors Targeting Human Carbonic Anhydrase

(129)Xe NMR biosensors are promising agents for the early detection of diseases, given that biomolecular interactions can perturb (129)Xe chemical shifts well beyond the typical field inhomogeneity of clinical MRI. We introduce human carbonic anhydrase (CA) as a single-binding-site enzyme for studyi...

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Detalhes bibliográficos
Main Authors: Chambers, Jennifer M., Hill, P. Aru, Aaron, Julie A., Han, Zhaohui, Christianson, David W., Kuzma, Nicholas N., Dmochowski, Ivan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629400/
https://ncbi.nlm.nih.gov/pubmed/19140795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806092w
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