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Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection

We report in this study that minimum productive HIV infection in astrocytes (a predominant cell type in brain and persists for the entire life) occurs through endocytosis. The lysosomotropic agent chloroquine enhanced permissiveness of astrocytes to HIV infection possibly by circumventing degradatio...

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Main Authors: Vijaykumar, Theophilus S., Nath, Avindra, Chauhan, Ashok
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629354/
https://ncbi.nlm.nih.gov/pubmed/18789806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.07.039
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