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Modeling the temporal evolution of the spindle assembly checkpoint and role of Aurora B kinase

Faithful separation of chromosomes prior to cell division at mitosis is a highly regulated process. One family of serine/threonine kinases that plays a central role in regulation is the Aurora family. Aurora B plays a role in the spindle assembly checkpoint, in part, by destabilizing the localizatio...

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Bibliografiske detaljer
Main Authors: Mistry, Hitesh B., MacCallum, David E., Jackson, Robert C., Chaplain, Mark A. J., Davidson, Fordyce A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629297/
https://ncbi.nlm.nih.gov/pubmed/19091947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810706106
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