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Slow peptide bond formation by proline and other N-alkylamino acids in translation
Proteins are made from 19 aa and, curiously, one N-alkylamino acid (“imino acid”), proline (Pro). Pro is thought to be incorporated by the translation apparatus at the same rate as the 19 aa, even though the alkyl group in Pro resides directly on the nitrogen nucleophile involved in peptide bond for...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629218/ https://ncbi.nlm.nih.gov/pubmed/19104062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809211106 |
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