Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation

Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, and fever and high rates of abortions in livestock. A nonstructural RVFV...

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Main Authors: Ikegami, Tetsuro, Narayanan, Krishna, Won, Sungyong, Kamitani, Wataru, Peters, C. J., Makino, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629125/
https://ncbi.nlm.nih.gov/pubmed/19197350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000287
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