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MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes

BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1) is the etiologic agent of a severe and fatal lymphoproliferative disease of mainly CD4(+ )T cell origin, adult T cell leukemia, which develops after prolonged viral persistence. Transformation of infected cells involves HTLV-1's oncoprotein...

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Autors principals: Pichler, Klemens, Schneider, Grit, Grassmann, Ralph
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628945/
https://ncbi.nlm.nih.gov/pubmed/19014482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-100
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