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Methylation-sensitive linking libraries enhance gene-enriched sequencing of complex genomes and map DNA methylation domains
BACKGROUND: Many plant genomes are resistant to whole-genome assembly due to an abundance of repetitive sequence, leading to the development of gene-rich sequencing techniques. Two such techniques are hypomethylated partial restriction (HMPR) and methylation spanning linker libraries (MSLL). These l...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628917/ https://ncbi.nlm.nih.gov/pubmed/19099592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-621 |
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