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A class frequency mixture model that adjusts for site-specific amino acid frequencies and improves inference of protein phylogeny
BACKGROUND: Widely used substitution models for proteins, such as the Jones-Taylor-Thornton (JTT) or Whelan and Goldman (WAG) models, are based on empirical amino acid interchange matrices estimated from databases of protein alignments that incorporate the average amino acid frequencies of the data...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628903/ https://ncbi.nlm.nih.gov/pubmed/19087270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-331 |
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