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Bayesian optimal discovery procedure for simultaneous significance testing

BACKGROUND: In high throughput screening, such as differential gene expression screening, drug sensitivity screening, and genome-wide RNAi screening, tens of thousands of tests need to be conducted simultaneously. However, the number of replicate measurements per test is extremely small, rarely exce...

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Autores principales: Cao, Jing, Xie, Xian-Jin, Zhang, Song, Whitehurst, Angelique, White, Michael A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628883/
https://ncbi.nlm.nih.gov/pubmed/19126217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-5
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