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Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells
BACKGROUND: Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound oxaliplatin has been extensively used in the treatment o...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628866/ https://ncbi.nlm.nih.gov/pubmed/19128511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-9-3 |
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