Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene

Persistently low white blood cell count (WBC) and neutrophil count is a well-described phenomenon in persons of African ancestry, whose etiology remains unknown. We recently used admixture mapping to identify an approximately 1-megabase region on chromosome 1, where ancestry status (African or Europ...

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Autors principals: Reich, David, Nalls, Michael A., Kao, W. H. Linda, Akylbekova, Ermeg L., Tandon, Arti, Patterson, Nick, Mullikin, James, Hsueh, Wen-Chi, Cheng, Ching-Yu, Coresh, Josef, Boerwinkle, Eric, Li, Man, Waliszewska, Alicja, Neubauer, Julie, Li, Rongling, Leak, Tennille S., Ekunwe, Lynette, Files, Joe C., Hardy, Cheryl L., Zmuda, Joseph M., Taylor, Herman A., Ziv, Elad, Harris, Tamara B., Wilson, James G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628742/
https://ncbi.nlm.nih.gov/pubmed/19180233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000360
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