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Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

MicroRNAs are short non-coding RNA molecules able to affect stability and/or translation of mRNA, thereby regulating the expression of genes involved in many biological processes. We report here that microRNAs miR-27a and miR-451 are involved in activating the expression of P-glycoprotein, the MDR1...

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Detalhes bibliográficos
Main Authors: Zhu, Hua, Wu, Hao, Liu, Xiuping, Evans, Brad R., Medina, Daniel J., Liu, Chang-Gong, Yang, Jin-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628586/
https://ncbi.nlm.nih.gov/pubmed/18619946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.06.007
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