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Domain-Oriented Reduction of Rule-Based Network Models

The coupling of membrane-bound receptors to transcriptional regulators and other effector functions is mediated by multi-domain proteins that form complex assemblies. The modularity of protein interactions lends itself to a rule-based description, in which species and reactions are generated by rule...

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Detalhes bibliográficos
Main Authors: Borisov, Nikolay M., Chistopolsky, Alexander S., Faeder, James R., Kholodenko, Boris N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628550/
https://ncbi.nlm.nih.gov/pubmed/19045829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb:20070081
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