Thiazolidinedione Therapy Is Not Associated with Increased Colonic Neoplasia Risk in Patients with Diabetes Mellitus

BACKGROUND & AIMS: Diabetes mellitus is associated with an increased risk of colorectal cancer. Thiazolidinediones, which are ligands for PPARγ, are widely used to treat patients with diabetes. PPARγ is highly expressed in the colon and exposure to thiazolidinediones has been proposed to affect...

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Bibliografiske detaljer
Main Authors: Lewis, James D., Capra, Angela M., Achacoso, Ninah S., Ferrara, Assiamira, Levin, Theodore R., Quesenberry, Charles P., Habel, Laurel A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628409/
https://ncbi.nlm.nih.gov/pubmed/18930061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.09.004
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