Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cells

Hepatitis C virus (HCV) primarily replicates within the liver, leading to hepatitis, fibrosis, and hepatocellular carcinoma. Infection is also associated with B-cell abnormalities, suggesting an association of the virus with B cells. The infectious JFH-1 strain of HCV can bind primary and immortaliz...

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Main Authors: Stamataki, Zania, Shannon-Lowe, Claire, Shaw, Jean, Mutimer, David, Rickinson, Alan B., Gordon, John, Adams, David H., Balfe, Peter, McKeating, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628366/
https://ncbi.nlm.nih.gov/pubmed/18838615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158824
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