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Both primitive and definitive blood cells are derived from Flk-1(+) mesoderm

Emerging evidence suggests that all hematopoietic and endothelial cells originate from Flk-1(+) mesoderm in the mouse. However, this concept has not been completely proven, especially for the origin of blood cells. Using either Flk1(+/Cre);Rosa26R-EYFP or Flk1(+/Cre);Rosa26R-LacZ mice, we permanentl...

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Autores principales: Lugus, Jesse J., Park, Changwon, Ma, Yunglin D., Choi, Kyunghee
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628363/
https://ncbi.nlm.nih.gov/pubmed/18957687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162750
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