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The role of Dickkopf-1 in bone development, homeostasis, and disease
Wnt/β-catenin signaling is central to bone development and homeostasis in adulthood and its deregulation is associated with bone pathologies. Dickkopf-1 (DKK1), a soluble inhibitor of Wnt/β-catenin signaling required for embryonic head development, regulates Wnt signaling by binding to the Wnt corec...
Sparad:
| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628360/ https://ncbi.nlm.nih.gov/pubmed/18687985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-145169 |
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