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Enantioselective Total Synthesis of Clavirolide C. Applications of Cu-Catalyzed Asymmetric Conjugate Additions and Ru-Catalyzed Ring-Closing Metathesis

The first enantioselective total synthesis of clavirolide C, a member of the dolabellane family of diterpenes isolated from Pacific soft coral Clavularia viridis, is disclosed. The total synthesis features the application of chiral amino acid-based ligands in Cu-catalyzed asymmetric conjugate additi...

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Detalhes bibliográficos
Main Authors: Brown, M. Kevin, Hoveyda, Amir H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628296/
https://ncbi.nlm.nih.gov/pubmed/18778057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8058414
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