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Design of Methylprednisolone Biodegradable Microspheres Intended for Intra-articular Administration

This study aimed to design methyprednisolone (MP)-loaded poly(d,l lactide-co-glycolide) (PLGA) microspheres (MS) intended for intra-articular administration. MP was encapsulated in four different types of PLGA by using an S/O/W technique. The effects of β-irradiation at the dose of 25 kGy were evalu...

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Detalhes bibliográficos
Main Authors: Cilurzo, Francesco, Selmin, Francesca, Minghetti, Paola, Montanari, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628272/
https://ncbi.nlm.nih.gov/pubmed/19009355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9158-1
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