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Co-solvent Evaporation Method for Enhancement of Solubility and Dissolution Rate of Poorly Aqueous Soluble Drug Simvastatin: In vitro–In vivo Evaluation

A number of synthesized chemical molecules suffer from low aqueous solubility problems. Enhancement of aqueous solubility, dissolution rate, and bioavailability of drug is a very challenging task in drug development. In the present study, solubility and dissolution of poorly aqueous soluble drug sim...

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Bibliografische gegevens
Hoofdauteurs: Pandya, Priyanka, Gattani, Surendra, Jain, Pankaj, Khirwal, Lokesh, Surana, Sanjay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628261/
https://ncbi.nlm.nih.gov/pubmed/19115110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9176-z
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