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Expression of Cyclooxygenase-2 and its Relationship to p53 Accumulation in Colorectal Cancers

PURPOSE: Cyclooxygenase (COX)-2 is an inducible isoform responsive to cytokines, mitogens, and growth factors, and is believed to be an important enzyme related to colorectal cancer (CRC). Existing evidence suggests that COX-2 expression is normally suppressed by wild-type p53 but not mutant p53, su...

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Main Authors: Lim, Sung-Chul, Lee, Tae-Beum, Choi, Cheol-Hee, Ryu, So-Yeon, Kim, Kyung-Jong, Min, Young-Don
格式: Artigo
語言:Inglês
出版: Yonsei University College of Medicine 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628091/
https://ncbi.nlm.nih.gov/pubmed/17594159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2007.48.3.495
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