Development of Monoclonal Antibodies Against Human IRF-5 and Their Use in Identifying the Binding of IRF-5 to Nuclear Import Proteins Karyopherin-α1 and -β1

PURPOSE: IRF-5 is a direct transducer of virus-mediated and TLR-mediated signaling pathways for the expression of cytokines and chemokines which form homodimers or heterodimers with IRF-7. However, direct IRF-5-specific monoclonal antibodies (mAbs) are not available at present. These could be used t...

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Autores principales: Yeon, Soo-In, Youn, Ju Ho, Lim, Mi Hwa, Lee, Hye Ja, Kim, Young Mok, Choi, Ji Eun, Lee, Jae Myun, Shin, Jeon-So
Formato: Artigo
Lenguaje:Inglês
Publicado: Yonsei University College of Medicine 2008
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628014/
https://ncbi.nlm.nih.gov/pubmed/19108028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2008.49.6.1023
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