Histo-Blood Group Gene Polymorphisms as Potential Genetic Modifiers of Infection and Cystic Fibrosis Lung Disease Severity

BACKGROUND: The pulmonary phenotype in cystic fibrosis (CF) is variable; thus, environmental and genetic factors likely contribute to clinical heterogeneity. We hypothesized that genetically determined ABO histo-blood group antigen (ABH) differences in glycosylation may lead to differences in microb...

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Detalhes bibliográficos
Main Authors: Taylor-Cousar, Jennifer L., Zariwala, Maimoona A., Burch, Lauranell H., Pace, Rhonda G., Drumm, Mitchell L., Calloway, Hollin, Fan, Haiying, Weston, Brent W., Wright, Fred A., Knowles, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627933/
https://ncbi.nlm.nih.gov/pubmed/19169360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004270
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