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Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis

BACKGROUND: Uncoupling protein 1 (UCP1) is a mitochondrial anion carrier, expressed in brown adipose tissue (BAT) of Eutherians. UCP1 is responsible for uncoupling mitochondrial proton transport from the production of ATP, thereby dissipating heat; it is essential for non-shivering thermogenesis (NS...

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Autors principals: Hughes, David A, Jastroch, Martin, Stoneking, Mark, Klingenspor, Martin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627829/
https://ncbi.nlm.nih.gov/pubmed/19128480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-4
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