Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

Since the discovery of leukemic stem cells (LSCs) over a decade ago, many of their critical biological properties have been elucidated, including their distinct replicative properties, cell surface phenotypes, their increased resistance to chemo-therapeutic drugs and the involvement of growth-promot...

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Bibliografiske detaljer
Main Authors: Misaghian, N, Ligresti, G, Steelman, LS, Bertrand, FE, Bäsecke, J, Libra, M, Nicoletti, F, Stivala, F, Milella, M, Tafuri, A, Cervello, M, Martelli, AM, McCubrey, JA
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627788/
https://ncbi.nlm.nih.gov/pubmed/18800146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.246
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