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Direct Transition-Metal-Free Intramolecular Arylation of Phenols
[Image: see text] Direct transition-metal-free, base-mediated intramolecular arylation of phenols with aryl halides has been developed. In the presence of 2.5 equivalents of t-BuOK in dioxane at 140 °C, the intramolecular cyclization of 3-(2-halobenzyloxy)phenols affords 6H-benzo[c]chromenes in high...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
2008
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2627406/ https://ncbi.nlm.nih.gov/pubmed/18798647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol801897m |
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