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GATA-4 and GATA-5 Transcription Factor Genes and Potential Downstream Antitumor Target Genes Are Epigenetically Silenced in Colorectal and Gastric Cancer

The GATA family of transcription factors participates in gastrointestinal (GI) development. Increases in GATA-4 and -5 expression occur in differentiation and GATA-6 expression in proliferation in embryonic and adult settings. We now show that in colorectal cancer (CRC) and gastric cancer promoter h...

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Publicat a:Mol Cell Biol
Autors principals: Akiyama, Yoshimitsu, Watkins, Neil, Suzuki, Hiromu, Jair, Kam-Wing, van Engeland, Manon, Esteller, Manel, Sakai, Hidekazu, Ren, Chun-Yan, Yuasa, Yasuhito, Herman, James G., Baylin, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262684/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.23.8429-8439.2003
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