Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy

Pathophysiological cardiac hypertrophy is one of the most common causes of heart failure. Epoxyeicosatrienoic acids, hydrolyzed and degraded by soluble epoxide hydrolase (sEH), can function as endothelium-derived hyperpolarizing factors to induce dilation of coronary arteries and thus are cardioprot...

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Autori principali: Ai, Ding, Pang, Wei, Li, Nan, Xu, Ming, Jones, Paul D., Yang, Jun, Zhang, Youyi, Chiamvimonvat, Nipavan, Shyy, John Y.-J., Hammock, Bruce D., Zhu, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626743/
https://ncbi.nlm.nih.gov/pubmed/19126686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811022106
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